Minggu, 07 Desember 2008

More about morning after pill

The post-coital contraception or emergency contraception, also called the morning after pill, uses several methods whose purpose is to oppose the implantation of recently fertilized egg .

After a condom accident or you forget to take anti-pregnancy pill? It is now possible to greatly reduce the risk of unwanted pregnancy with the morning after pill.

Hormonal methods
Hormonal methods remain the most used because they are easy to implement and do not require hospitalization.

Treatment required since November 2004 by taking only one pill. The effectiveness of treatment is much greater if taken right after unprotected sex. That is why the tablet should be taken as soon as possible, if possible within 12 hours after unprotected sex, and within 72 hours (3 days) at the latest.

The principle of this emergency contraception is to block ovulation and alter the uterine lining to make it unfit for implantation.

Contraception of NorLevo is vailable free in pharmacies (and issued free of charge and anonymously to minors).

Warning: These medicines should only be used occasionally because they can severely disrupt the menstrual cycle. They are not effective methods of contraception and especially they do not protect the risk of transmission of sexually transmitted diseases. Only condoms enables effective protection against STDs.
RU 486

Mifepristone (RU 486) has received much attention during its launch where it had been called abortion pill. It is has a strong antiprogestin activity. It is currently used in abortion drug and also to trigger delivery in therapeutic abortion. It is being evaluated in other indications and especially in the post-coital contraception. Two possibilities were considered: the prescription pill within 72 hours after intercourse, or taking pills at the end of the cycle.

The IUD
The use of intrauterine device (IUD) in the hours following sex may offer protection efficiency of nearly 100%. The limits of this method are mainly related to the fact that the candidates are young women, often without children and with statistically high risk of sexually transmitted disease. An IUD in this case may lead to a major pelvic infection.

Note
All these methods are still emergency techniques that do not replace traditional contraceptions.

Short Instruction on morning-after pill

You had a "condom accident" or forgot to take anti-pregnanct pill? What to do? Do not stand idly, do not wait. It is possible to greatly reduce the risk of unwanted pregnancy by using morning-after pill or post-coital contraception.

What is it?
The pill uses progestin hormonal method and should be used to provide protection in emergencies. A few years ago there is a proof of connection between estrogen and progestin, Tetragynon® was withdrawn from the market in 2004 because of its greater number of indications and has lower tolerance.

NorLevo includes one pill that contains only progestin. Take this pill tjis pill right after sex. The longer you wait, its effectiveness declines.

These methods are made to protect from pregnancy, for sex that have occurred within 72 hours.

When and how to use these morning-after pills?
We must use these treatments as soon as possible and no later than three days after a sex not or poorly protected sex. They are effective in about 75% of cases, especially if the pills are taken early.


What will happen then?
Within hours of taking pills, you may feel nausea - in 25% of cases - even vomiting may occur.
Taking the morning-after pill cannot stop a pregnancy that already happen.

Although frequent use of these pills in the next day does not pose a medical problem, it is obviously preferable to opt for a classic hormonal contraception which, taken properly, will be much more effective.

A Short History of Morning After Pill on France

While pills and condoms are widely used in France, the number of abortions remains very high and emergency contraception, like morning after pill is under-utilized.

Morning after pill is now available in pharmacies without a prescription and anonymously and free for minors.

Women face real difficulties in the daily management of contraception, for emotional, social, sexual reasons.

  • Emergency Contraception France is a country where contraception is the most widely used: 63% of women 18 to 44 years using a contraceptive method. However, two thirds of abortions (abortions) are practiced among these women (21% using the pill and condoms 12%);
  • Only 6% of women using oral contraceptives use morning after pill after a forgot to take anti-pregnancy pill and 42% after bad use of condom
  • 30 to 36% of pregnancies are unwanted and 20% of pregnancies lead to abortion (more than 200 000 abortions for 760 000 births each year).
  • An estimated 10% of women of childbearing age are likely to use morning after pill at some point in their lives. In fact, only 3% adopt this approach.

If the use of morning after pill is becoming more common, various surveys show however its under-utilization, lack of information or awareness of the risk of pregnancy.

  • Over 800 000 NorLevo boxes were sold between June 2003 and June 2004. These figures reflect an increase of 10% over the previous year;
  • 95% of boxes were purchased in pharmacies without a prescription. The rest was issued on medical prescription or nurses or school free of charge to minors;
  • The issuance by school nurses represents 15 000 boxes per year, and 75% of high school students come from minor;
  • The effectiveness of morning after pill is 95% if the taking occurs within 24 hours after sexual intercourse, 85% between 24 and 48 hours and 58% between 48 and 72 hours

A guide to Morning After Pill


Definition and characteristics:

It is a unique method that avoids the occurrence of an unwanted pregnancy after a sexual or poorly protected intercourse, ie in the absence of contraception or in case of failure the basic contraceptive methods used.

* This method consists of taking the contraceptive taken in two doses:
o The first dose must be taken as soon as possible, which is why it is called emergency contraception.
o The second dose, 12 to 24 hours after the initial dose.
* Emergency contraception must be used only in exceptional cases.
* It is reserved for emergencies
* It does not prevent pregnancy in all cases (failure in 5 to 42% of cases).
* It is not a substitute for regular contraception because it causes undesirable hormonal overdose if taken regularly.
* This is not a method of abortion


In what situations should you use morning after pills?

After all unprotected sex if you do not want to be pregnant. Here are some examples:

+ After sex, then you have not taken any contraceptive method;
+ When you have a problem with condom (badly placed, or torn or not properly withdrawn);
+ After forget to take your pill:
# If delayed more than 3 hours in case you use a pill microprogestative;
# If delayed more than 12 hours in case you use a pill oestrogens and progestin.
+ In case of late withdrawal of penis, if not using condom;
+ In case of rape.

How does it work?
The mode of action is unknown but it is possible that emergency contraception can block or delay ovulation, prevent fertilization or the implantation of a fertilized egg by inducing changes in the endometrium making it unsuitable for implantation; it is therefore good before implantation in the uterus. This is not an abortion, If the pregnancy is already underway, the emergency contraception can no longer act, the pregnancy is proceeding normally.


When the cycle can use
# The emergency contraception can be used at any time cycle given the uncertain date of ovulation, fertilization can occur anytime after sex. Any unprotected sex therefore a risk of pregnancy,
# It is also recommended for use with basic contraceptions (condoms, spermicides, cervical caps ...) until the resumption of the next plateau, including during menstruation.

# It is not recommended to use several times the emergency contraceptive during the same menstrual cycle because of the possibility of significant disturbance of the cycle.



Contra-indication of morning after pills:

# Those few women who are allergic to one of its components,
# It is not recommended for women at risk of ectopic pregnancy because it is unclear whether this method of contraception may prevent implantation of an ectopic pregnancy and prevent an ectopic pregnancy to continue to develop.

Side effects of morning after pills:
Some women may experience nausea and rare vomiting, dizziness, fatigue, headaches, lower abdominal pain, feeling of tension breasts and vaginal bleeding.


Morning After Pill effectiveness:
# It depends on how fast you take the morning after pill. If taken within 12 to 24 hours after sex, its effectiveness is 95% and decreases during the next 2 days:

# 85% between 24 and 48 hours:
# 58% between 48 and 72 hours
# Efficiency unknown after 72 hours

# It is not effective in all cases;
# In case of vomiting in the first three hours after taking a dose of emergency contraception, it is recommended to immediately resume a new dose of medicine.
# The rules generally occur as scheduled;
# In some, it is of spotting or metrorrhagia of which may persist until the next following rules
# In cases where

* The rules have more than 5 days late,
* The Metrorrhagia outside the rules
* Abnormal bleeding on the scheduled date of the rules (rules like no others)
* Abdominal pain
* Signs of pregnancy

it is necessary to take a pregnancy test and consult a doctor as pregnancy intra-uterine or ectopic pregnancy are possible.

What if the 72 hours is exceeded?

# After the first 72 hours (3 days), if you had taken the emergency contraceptive while you were pregnant without knowing it, the emergency contraceptive would be ineffective because it does not work if pregnancy has already begun.


Remember that the morning-after pill does not protect against sexually transmitted diseases, including AIDS.
How and when to take the emergency contraceptive

There are two types of emergency contraceptives:

1 - The emergency contraceptive progestin (levonorgestrel 0.75 mg): two tablets:

* This treatment has been simplified, there is currently a single dose with two tablets, oral, taken as soon as possible, if possible within 12 hours, and no later than 72 hours after unprotected sex.

This medicine may be issued without a prescription and is not reimbursed, but it may also be prescribed and then returned to 65%. Pharmacy, it is issued to minors without a prescription and free.

2 - The emergency contraceptive oestrogens and progestin (levonorgestrel 0.25 mg + 0.5 mg ethinyl): four tablets: The pregnancy rate is about 1 to 2% (failure rate).

* The first two pills as soon as possible after sex and no later than 72 hours after the report;
* The other two tablets within 12 to 24 hours after the first two tablets.

Morning After Pill FAQ

What is emergency contraception?

Emergency contraception is a measure that aims to prevent pregnancy after unprotected sex.

How should we use ECPs?

a) Combined oral contraceptives

Each dose contains at least 0.1 mg to 0.5 mg ethinyl estradiol and levonorgestrel. The first dose (4 pills with low dose pills or 2 high dose) must be taken within 72 hours after unprotected sex. Then repeat the same dose 12 hours later.

b) progestin pills

Each dose contains at least 0.75 mg of levonorgestrel. The first dose (one pill specially formulated for emergency contraception or 20 regular progestin pills) must be taken within 72 hours after unprotected sex. Then repeat the same dose 12 hours later.

What is the mechanism of action of ECPs?

Emergency contraceptive pills do not disturb established pregnancy. The ECPs varies with the menstrual cycle phase. They are presumed power:

* Remove or delaying ovulation
* Acting after ovulation

When to use ECPs?

They should be started within 72 hours after the reports, when:

* No contraceptive has been used
* The contraceptive fails (eg breakage or slippage of condoms)
* The contraceptive is used incorrectly (eg forgetting to take the pill)
* The woman has been raped or forced

The effectiveness of ECPs after unprotected sex is all the greater they are administered quickly.

Who can use ECPs?

Any woman of reproductive age who has unprotected sex and who:

* Does not want to get pregnant
* Did not against indications

Benefits

* Safe, effective and easy to use
* Use at any time during the menstrual cycle
* Pills available in most places
* Provision possible without a prescription
* No consultation or medical examination required

Disadvantages

* No protection against STDs
* Side effects in the short term

Possible side effects

* Nausea
* Vomiting
* Headaches
* Dizziness
* Fatigue
* Voltage breast

Side effects are much more frequent with oral contraceptives combined with progestin pills. They generally persist until 24 hours after administration of second dose.

Counseling
* Any symptom or concern score
* Common Side Effects
* Need a method of contraception
* Prevention of STD and HIV

Dispelling myths about ECPs
Emergency contraceptive pills:

* DO NOT cause abortion
* Have no adverse effects on pregnancy

Morning After Pill: an important option for young adults


Young women under 24 years are more likely than older ones to experience unwanted pregnancy, even when contraceptives were readily available. Several factors explain this situation. Sex between young adults may be occasional and not prévus.1 Young married and unmarried are often inefficient users of contraceptives because they just started sexual practices and regulatory naissances.2 Often, they are misinformed on sexuality and reproductive health. Perhaps they are authentic to some myths, for example that a woman can not get pregnant the first time she has sex.

The emergency contraceptive pills (ECPs), a contraceptive that can be used up to 72 hours after unprotected sex, can be very useful for young adults. Since the PCU avoid unwanted pregnancy, it also helps to avoid abortion and the maternal morbidity and mortality. The PCU helps sexually active young people to realize that it is perhaps time for them to start using a regular contraception.3 It is important that young men and women, know the PCU because they have unprotected sex and pregnancy may not soubaitée with all health and social consequences that entails, they know there is still time to do something to prevent this situation.

What the emergency contraceptive pill and how does it work?

The PCU contains a special dose of the same hormones as the pill normal. It is reserved for emergencies that may arise, for example if a condom breaks or a diaphragm did not remain in place or no use of contraception or rape. A woman who uses the PCU takes two doses to twelve hour intervals, with special strengths of regular oral contraceptives containing estrogen normally and progestatifs.4 Another progestin pills, as effective as combined oral contraceptives but with a lower incidence of side effects is also available in some countries. Whatever the protocol, the first is taken as quickly as possible after unprotected sex but no later than within 72 hours.

The PCU decreases by about 75% risk of pregnancy. This rate is calculated using estimates that if 100 women have one unprotected sexual intercourse during the second or third week of their menstrual cycle, only two fall pregnant if they use ECPs compared to the eight who normally fall pregnant without the use of this contraceptif.5

The instructional material such as training guide Pathfinder International provides detailed information on the formulation, dosage and clinical management of the emergency contraceptive pill .6 Some women have nausea and vomiting for one or two days following the capture of the PCU. Under other side effects, there is the saignotements a temporary sensitivity breasts, headaches, dizziness and fatigue.

Next at what point in its cycle, a woman uses the PCU act in different ways. Studies show that if ovulation has not yet occurred, ECPs can stop or postpone ovulation. The mechanism of delaying ovulation is probably the only mode of action or the main mode. Some researchers believe that ECPs can also act in other ways but there are few facts to support their hypothèse.7 If a woman has ovulation, ECPs can prevent fertilization, prevent the transport of a fertilized egg in the tube Fallopian making it reaches the uterus at the wrong time or they may prevent implantation in the uterus .8 Additional research is needed to determine which of these mechanisms actually contributes to the effectiveness of CEP.

ECPs can not cause an abortion. According to the definition of the medical community and regulatory agencies like the U.S. Administration for food and medicine, pregnancy begins after implantation of an egg fécondé.9 ECPs have no effect on an embryo implanted . If used in early pregnancy, the facts indicate that they have no harmful effect for the mother or foetus.10

What are the benefits of the PCU for young people?

*

The CEP offers a substantial because it is a method in case of non-sexual protégées.11Pour young people who are not prepared for a sexual encounter or have unintended reports, the CEP offers a second chance to use a contraceptive.
*

The PCU is for the young who had not yet seen an introduction of services to health care reproductive.12
*

Family planning programs can provide ECPs and advice to young sexually active before they may need to use them in an emergency or within 72 hours after unprotected sex. A distribution in advance with the advice and monitoring requirements are especially important for young people using methods barriers whose failure rates are higher than those of hormonal contraceptives. Some experts of the reproductive health of young advocates to distribute a leaflet PCU with condoms and vice versa.13
*

ECPs help sexually active young people while they make the transition and move to a sustainable use of contraceptifs.14 ECPs should be seen as a transitional contraceptives because regular rates much higher efficiency. For example, the rate of unwanted pregnancy for condoms, as commonly used, is about 14% of women during the first year of use .15

What are the disadvantages of the PCU?

*

Like all hormonal methods, the PCU does not protect against STDs, including HIV.
*

Considering that many women probably n'agiront if they do not have their next period, they miss the opportunity to use the PCU to prevent grossesse.16
*

Since the PCU is only effective within 72 hours after unprotected sex, it should be clear to young people a means of contraception is necessary for future sex. The CEP offers no protection for the remainder of the menstrual cycle a woman.

What are the experiences of ECPs distributing the programs for youth?

The use of the PCU is limited in many countries, although the medical community known for thirty years the effectiveness of the pill in an emergency .17 Despite these limitations, more and more women hear about the PCU and ask their provider to provide them. In most countries, women can obtain ECPs only through the service, although in some countries, platelets pill can be obtained without a prescription at pharmacies or from the community.

Some European countries, such as the United Kingdom, selling plates of pills packaged specifically for use in an emergency .18 Women commonly use the PCU in the UK and the Netherlands where the pill is part of integrated reproductive health reimbursed by social security pays.19 The experience of the Netherlands demonstrates the acceptability of the PCU among young people: in 1991, 70% of Dutch women receiving PCU their general were less 25 years and 34% had less than 20 ans.20

Cost data from the United Kingdom indicate that the provision of the PCU with advice costs between $ 19 and $ 74, depending on prestataire.21 In developing countries, we think the price will be about 25 cents for non-governmental organizations, NGOs and marketing social.22

What are the barriers to the use of ECPs by young adults?

Despite the importance and effectiveness of the PCU, young people who need emergency contraception face many barriers to get it. Many young people are not aware of the PCU as a means of preventing unwanted pregnancy. The health care providers are often themselves as poorly informed about emergency contraception and the argument often put forward by the PCU encourages promiscuity as a reason not to distribute to young then that is not coming back this reason.

*

Most providers in a study in Viet Nam have overestimated the incidence and severity of side effects and cited indications against incorrect. Some providers said they did not propose the PCU to their patients given the lack of research results known and most thought that the distribution should be strictly contrôlée.23
*

Some confusion still surrounds the PCU and abortion and this confusion may block efforts to prevent an unwanted pregnancy, as we saw in Malaisie.24
*

Some recommend to provide the PCU combined with condoms but a study of university hospitals in the United States shows that some providers are concerned about this approach. These providers believe that tell students to use condoms to prevent pregnancy and STDs and then provide them with the PCU as the condom may tear is an ambiguous message about the effectiveness of condoms.25

PCU programs are underway in developing countries?

Despite such barriers, family planning programs involved in seeking international awareness of the PCU and make them available. For example, the organization affiliated to the International Federation for Family Planning in Colombia, PROFAMILIA organizes daily educational activities for youth, their parents and teachers. Educators give information on the PCU in their meetings on reproductive health. Young people want to know what is in the PCU, how it works, causes Does abortion, what are the risks or side effects and is permitted by law. The staff PROFAMILIA shows young people how to use ECPs only for emergencies and encourages them to share information on PCU with their camarades.26

But most programs that distribute the PCU youth in developing contexts are still at the pilot stage. They do not emit enough information or data on their experience. But the examples of these new programs will remain.

*

The research unit on fertility at the Faculty of Medicine of Ibadan in Nigeria began a three-year pilot project in six centers for family planning and reproductive health. The clinic Youth Association for reproductive health and family (ARFH) is one of those sites. Grace Delano ARFH the pill called "saving" 27dans its support to the project's purpose is to broaden access to ECPs, especially among young people aged 15 to 24 ans.28 Even young men come to consult the clinics to receive ARFH PCU for their partner. Counselors ARFH advantage of the opportunity to tell young people that we should not rely on this method of emergency, it is better to avoid anxiety about a possible pregnancy and sexually young assets should adopt a regular contraceptive method.
*

The Medical Association of Women of Kenya and the Program for Appropriate Technology in Health (PATH) wrote a short story, "What young people need to know about emergency contraception." The story begins with a young woman who cares about being pregnant after having the first sexual intercourse. Fortunately, the mother of the girl discovers what happened and give her daughter the necessary information on ovulation and fertilization. At the insistence of his mother, the girl went to a doctor for the PCU and avoid a possible pregnancy and promises not to have sex until marriage. The story ends by encouraging young people to spread the news about emergency contraception with their friends who have had unprotected sex protégés.29
*

The Medical Center in Mexico City as part of the National University of Mexico has a pilot project with the Population Council offering students advice and medical services necessary for PCU.30 In addition, the Mexican Foundation for Family Planning (MEXFAM) and the Mexican Institute for research on family and population (IMIFAP) brought together information materials in Spanish for young people dealing with the PCU and communicated via publications and the Internet .31

What is the final message?

The CEP is an important option for emergency contraception for young people who are sexually active. Given the barriers surrounding the issue of youth sexuality and the confusion between the PCU and abortion, the PCU is underused. When the PCU is available and accessible to young, it is well accepted. It helps reduce the incidence of unwanted pregnancies and abortions, especially if its distribution is good advice. It also helps young people to realize the significance of contraception and encourages them to use a more reliable method on a regular basis.